Meat sauce and Bolognese are both meat-based sauces used in Italian cuisine. However, the key difference between the two is the type and amount of meat used. Meat sauce is characterized by a finely ground or chopped meat like ground beef or turkey, while Bolognese is made with a slow-cooked mixture of ground meat, usually beef or a combination of beef, pork, and veal. Additionally, Bolognese usually includes vegetables like carrots, celery, and onions, and is simmered for several hours with red wine and a small amount of tomato paste, resulting in a rich, flavorful sauce. Meat sauce, on the other hand, is typically made with tomato sauce or diced tomatoes, herbs, and spices.